From: Failure of non-invasive ventilation in patients with acute lung injury: observational cohort study
NIPPV failure (n = 38) | NIPPV success (n = 16) | p value | |
---|---|---|---|
Initial mode of ventilation | |||
Bi-level NIPPV | 21 | 8 | 0.72 |
CPAP | 172 | 84 | |
Respiratory rate (initial; breaths/minute) | 31 (24–39) | 23 (21–34) | 0.13 |
Tidal volume (ml; n = 27) | 640 (493–700) | 435 (384–558) | 0.03 |
Minute ventilation (l/minute; n = 27) | 17.2 (12–27) | 12.5 (8–14) | 0.02 |
Tidal volume (ml/kg predicted body weight; n = 27) | 9 (7.5–11) | 8.4 (6.4–10.4) | 0.34 |
IPAP (cmH2O; n = 29) | 12 (10–16) | 13 (12–15) | 0.53 |
EPAP or CPAP (cmH2O; n = 43) | 5 (5–7.5) | 5.5 (5–8) | 0.92 |
Decrease in respiratory rate after NIPPVa | 13 (34%) | 9 (56%) | 0.24 |
Improvement in arterial blood gas PaO2/FiO2 after the NIPPVb | 7 (18%) | 6 (38%) | 0.17 |