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Table 2 Non-invasive positive pressure ventilation parameters

From: Failure of non-invasive ventilation in patients with acute lung injury: observational cohort study

 

NIPPV failure (n = 38)

NIPPV success (n = 16)

p value

Initial mode of ventilation

   

   Bi-level NIPPV

21

8

0.72

   CPAP

172

84

 

Respiratory rate (initial; breaths/minute)

31 (24–39)

23 (21–34)

0.13

Tidal volume (ml; n = 27)

640 (493–700)

435 (384–558)

0.03

Minute ventilation (l/minute; n = 27)

17.2 (12–27)

12.5 (8–14)

0.02

Tidal volume (ml/kg predicted body weight; n = 27)

9 (7.5–11)

8.4 (6.4–10.4)

0.34

IPAP (cmH2O; n = 29)

12 (10–16)

13 (12–15)

0.53

EPAP or CPAP (cmH2O; n = 43)

5 (5–7.5)

5.5 (5–8)

0.92

Decrease in respiratory rate after NIPPVa

13 (34%)

9 (56%)

0.24

Improvement in arterial blood gas PaO2/FiO2 after the NIPPVb

7 (18%)

6 (38%)

0.17

  1. aRespiratory rate <30 and a 10% decrease from before the non-invasive positive pressure ventilation (NIPPV) institution. bImprovement in PaO2/FiO2 >10 units after the start of NIPPV (within one hour). Patients who were intubated before the follow up blood gas measurement were considered not to have improvement. APACHE, Acute physiology and chronic health evaluation; CPAP, continuous positive airway pressure; EPAP, expiratory positive airway pressure; IPAP, inspiratory positive airway pressure. PaO2/FiO2, ratio of arterial partial pressure of O2 and inspired O2 concentration;