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Table 1 Clinical characteristics of medical ICU patients with ALI receiving NIPPV.

From: Failure of non-invasive ventilation in patients with acute lung injury: observational cohort study

 

NIPPV failure (n = 38)

NIPPV success (n = 16)

p value

Age

64 (54.7–73.2)

60 (46.2–83.7)

0.86

Female gender

13 (34%)

8 (50%)

0.27

APACHE III score

81.5 (64–103.5)

55.5 (43–73.75)

<0.01

SOFA score

8.5 (6–11)

5.5 (3.25–7.75)

<0.01

Sepsis

33 (87%)

14 (88%)

0.90

Shock

19 (100%)

0 (0%)

-

Transfusion

11 (29%)

5 (31%)

0.80

Aspiration

14 (37%)

6 (38%)

0.90

Immunosuppression

18 (47%)

5 (31%)

0.37

PaO2/FiO2

112 (70–157)

147 (118–209)

0.02

PaCO2

36 (32–44)

42 (36–48)

0.10

pH

7.37 (7.26–7.43)

7.39 (7.32–7.45)

0.40

Base excess

-4.0 (-7–0.02)

0.5 (-3–1.3)

0.01

Lactate (n = 37)

2.1 (1.2–4.0)

1.5 (1.2–2.1)

0.26

  1. ALI, acute lung injury; APACHE, Acute Physiology and Chronic Health Assessment; ICU, intensive care unit; NIPPV, non-invasive positive pressure ventilation. PaO2/FiO2, ratio of arterial partial pressure of O2 and inspired O2 concentration; SOFA, Sequential Organ Failure Assessment, PaCO2, arterial partial pressure of CO2