Table 1 Clinical characteristics of patients with ventilator-associated pneumonia enrolled in the study categorized according to the ACCP/SCCM classification.
Characteristic | Sepsis | Severe sepsis | Septic shock |
|---|---|---|---|
Number of patients | 27 | 27 | 36 |
Age (years, mean ± SD) | 52.6 ± 20.8 | 67.7 ± 13.6 | 58.0 ± 18.1 |
Male/female | 20/7 | 18/9 | 27/9 |
APACHE II score (mean ± SD) | 15.63 ± 6.06 | 17.88 ± 4.19 | 19.40 ± 7.03* |
Sequential Organ Failure Assessment score (mean ± SD) | 5.78 ± 2.82 | 7.21 ± 2.83 | 9.54 ± 4.10† |
White blood cells (/μl, mean ± SD) | 12.132,6 ± 5.060,7 | 13.850,0 ± 7.026,9 | 14.206,0 ± 8.683,0 |
Underlying conditions [n (%)] | |||
Multiple trauma | 8 (29.62) | 1 (3.70) | 9 (25.00) |
Brain haemorrhage | 6 (22.22) | 7 (25.92) | 3 (8.33) |
Respiratory failure due to chronic obstructive pulmonary diseases | 8 (29.62) | 8 (29.62) | 11 (30.55) |
Acute abdomen | 1 (3.70) | 2 (7.41) | 4 (11.11) |
Celiac aorta aneurysm replacement | - | 2 (7.41) | 3 (8.33) |
Others | 4 (14.81) | 7 (25.92) | 6 (16.66) |
Predisposing factors [n (%)] | |||
Diabetes mellitus type 2 | 4 (14.81) | 4 (14.81) | 6 (16.66) |
Coronary heart disease | 3 (11.11) | 8 (29.62) | 4 (11.11) |
Hypertension | 2 (7.41) | 6 (22.22) | 4 (11.11) |
Others | 6 (22.22) | - | 8 (22.22) |
Pathogens [n (%)] | |||
Acinetobacter baumannii | 10 (37.03) | 11 (40.74) | 16 (44.44) |
Pseudomonas aeruginosa | 5 (18.51) | 7 (25.92) | 4 (11.11) |
Others | 2 (7.41) | 3 (11.11) | 2 (5.55) |
Bacteraemia [n (%)] | 4 (14.81) | 3 (11.11) | 5 (13.88) |
Case fatality [n (%)] | 6 (22.2) | 9 (33.3) | 18 (50.0) |