Table 4 Microbiologic documentation available in visit 2 in modified intention-to-treat patients with nosocomial pneumonia

Pathogens (%)

0.002

   None

27.5

51.8

52.5

   Monomicrobial

33.3

29.0

29.9

   Polymicrobial

39.2

19.2

23.8

Yield of microbial investigations (%)

   Tracheal aspirate

87.5

79.5

81.4

81.6

   Protected specimen brush

96.3

67.9

80.0

32.8

   Bronchoalveolar lavage

100

71.4

77.5

4.1

Pathogens identified (all patients)

   Monomicrobial

17

56

73

0.02

Pseudomonas aeruginosa

1

13

14

Other Pseudomonas

0

2

2

Acinetobacter baumannii

0

11

11

Other Acinetobacter

0

1

1

Enterobacteriaceae

3

12

15

Staphylococcus aureus

4

9

13

Haemophylus influenzae

6

5

11

Streptococcus pneumoniae

2

2

4

Streptococcus viridans group

0

0

0

Other

1

1

2

   Polymicrobial

20

38

58

<0.001

Mixed, including NFGNB and methicillin-resistant S. aureus

4

23

27

H. influenzae plus Streptococcus spp.

9

2

11

Other

7

13

20

Pathogens identified (Group V^a)

   Monomicrobial

1

7

8

P. aeruginosa

1

2

3

Other NFGNB

0

2

2

Enterobacteriaceae

0

1

1

Methicillin-resistant S. aureus

0

1

1

Other

0

1

1

   Polymicrobial

4

11

15

Mixed, including NFGNB and methicillin-resistant S. aureus

1

8

9

Other

3

3

6