| Hazard ratio (95% confidence interval) | P |
---|---|---|
Panel A: association of AKI, defined by meeting any RIFLE criteria, with mortality | Â | Â |
AKI (reference no AKI) | 1.7 (1.28–2.13) | < 0.001 |
SOFAnonrenal score (per point) | 1.1 (1.10–1.15) | < 0.001 |
Age (per 10 years) | 1.1 (1.07–1.18) | < 0.001 |
Sex (female) | 0.9 (0.78–1.07) | 0.252 |
Race (reference white) | Â | 0.528 |
   Black | 1.1 (0.88–1.45) | 0.324 |
   Other | 0.8 (0.41–1.68) | 0.608 |
Medical admission (reference surgical admission) | 2.9 (2.44–3.40) | < 0.001 |
Main reason for admission (reference cardiovascular disease) | Â | < 0.001 |
   Trauma | 0.9 (0.66–1.09) | 0.196 |
   Neurological disease | 1.3 (1.03–1.52) | 0.026 |
   Pulmonary disease, infection | 0.8 (0.65–1.03) | 0.087 |
   Gastrointestinal disease | 0.5 (0.21–1.25) | 0.140 |
   Malignancy | 0.2 (0.04–0.63) | 0.009 |
   Other | 0.4 (0.22–0.62) | < 0.001 |
Panel B: association of maximum RIFLE class with mortality | Â | Â |
RIFLEmax (reference no AKI) | Â | < 0.001 |
   Risk | 1.0 (0.68–1.56) | 0.896 |
   Injury | 1.4 (1.02–1.88) | 0.037 |
   Failure | 2.7 (2.03–3.55) | < 0.001 |
SOFAnonrenal score (per point) | 1.1 (1.10–1.14) | < 0.001 |
Age (per 10 years) | 1.1 (1.08–1.20) | < 0.001 |
Sex (female) | 0.9 (0.76–1.06) | 0.190 |
Race (reference white) | Â | 0.673 |
   Black | 1.1 (0.87–1.45) | 0.389 |
   Other | 0.9 (0.44–1.97) | 0.844 |
Medical admission (reference surgical admission) | 2.7 (2.27–3.21) | < 0.001 |
Main reason for admission (reference cardiovascular disease) | Â | < 0.001 |
   Trauma | 0.9 (0.69–1.18) | 0.463 |
   Neurological disease | 1.3 (1.06–1.60) | 0.011 |
   Pulmonary disease, infection | 0.8 (0.66–1.07) | 0.154 |
   Gastrointestinal disease | 0.6 (0.24–1.41) | 0.230 |
   Malignancy | 0.2 (0.04–0.69) | 0.013 |
   Other | 0.3 (0.20–0.60 | < 0.001 |