Table 3 Therapeutic interventions and changes in perfusion variables during optimization

Intraoperatively

   Operation time (min)

315 ± 109

331 ± 132

   Total volume (l/hour)

1.31 ± 0.54 (0.97/1.21/1.54)

1.35 ± 0.43 (1.05/1.29/1.65)

   Red blood cells (ml)

609 ± 244 (480/600/600)

713 ± 458 (500/600/650)

   Number of transfused patients (%)

11 (44%)

12 (48%)

   Dobutamine doses (μg/kg/minute)

3.5 ± 0.7

5.5 ± 1.8

   Dobutamine (number of patients)

2 (8%)

25 (100%)*

   Initial serum lactate (mEq/l)

1.3 ± 0.6

1.3 ± 0.5

   Final serum lactate (mEq/l)

1.7 ± 0.7

1.9 ± 0.9

   Initial mixed venous oxygen saturation

83 ± 4

81 ± 6

   Final mixed venous oxygen saturation

86 ± 4

86 ± 7

   Number of goal-achievers

7 (28%)

21 (84%)*

Intensive care unit

   Total volume (l/hours)

0.29 ± 0.12

0.28 ± 0.18

   Red blood cells (ml)

1064 ± 684 (450/600/900)

650 ± 226* (600/600/600)

   Number of transfused patients (%)

7 (28%)

6 (24%)

   Dobutamine doses (μg/kg/minute)

5.7 ± 2.3

6.1 ± 3.4

   Dobutamine (number of patients)

6 (24%)

20 (80%)*

   Sodium nitroprusside

6 (24%)

2 (8%)

   Initial serum lactate (mEq/l)

2.5 ± 1.6

2.2 ± 0.8

   Final serum lactate (mEq/l)

1.9 ± 2.0

1.3 ± 0.4

   Initial mixed venous oxygen saturation

76 ± 13

78 ± 9

   Final mixed venous oxygen saturation

78 ± 9

77 ± 8

   Number of goal-achievers

16 (64%)

22 (88%)*