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Table 2 Summary of the validity assessments of the randomized clinical trials of kinetic bed therapy

From: Kinetic bed therapy to prevent nosocomial pneumonia in mechanically ventilated patients: a systematic review and meta-analysis

Study Year Allocation concealment Blinding Intention-to-treat analysis Explicit definition of pneumonia Features used to define of pneumonia
Ahrens [17] 2004 No No No Yes C, F, L, SA, H, BC, PC
Bhazad [29] 2002 Yes No No No Nil
Kirschenbaum [23] 2002 No Yes No Yes C, F, SC, BQ
Macintyre [7] 1999 No Yes No Yes C, F, L, SA, BQ
Gietzen [30] 1996 No No No No Nil
Traver [27] 1995 No Yes No Yes C, F, L
Whiteman [28] 1995 Yes Yes No Yes C, F, L, SA, SC
deBloisbanc [19] 1993 Yes Yes No Yes C, F, SA
Nelson [24] 1992 No No No Yes C, F, L, SA
Shapiro [25] 1992 No No No No Nil
Clemmer [18] 1990 Yes Yes No No Nil
Fink [21] 1990 Yes No Yes Yes C, F, SA, SC
Demarest [20] 1989 Yes No No Yes C, F, SA
Summer [26] 1989 No Yes No Yes C, F, L, SA
Gentilello [22] 1988 Yes No No Yes C, F, L, SA, SC
  1. BC, blood culture; BQ, bronchoalveolar lavage with quantitative culture; C, persistent new changes on chest radiograph; F, fever; H, histologic evidence of pneumonia in lung tissue; L, leukocytosis or leukopaenia; PC, pleural fluid culture; SA, altered sputum appearance; SC, positive sputum culture.