Kinetic bed therapy to prevent nosocomial pneumonia in mechanically ventilated patients: a systematic review and meta-analysis

Table 2 Summary of the validity assessments of the randomized clinical trials of kinetic bed therapy

Study	Year	Allocation concealment	Blinding	Intention-to-treat analysis	Explicit definition of pneumonia	Features used to define of pneumonia
Ahrens [17]	2004	No	No	No	Yes	C, F, L, SA, H, BC, PC
Bhazad [29]	2002	Yes	No	No	No	Nil
Kirschenbaum [23]	2002	No	Yes	No	Yes	C, F, SC, BQ
Macintyre [7]	1999	No	Yes	No	Yes	C, F, L, SA, BQ
Gietzen [30]	1996	No	No	No	No	Nil
Traver [27]	1995	No	Yes	No	Yes	C, F, L
Whiteman [28]	1995	Yes	Yes	No	Yes	C, F, L, SA, SC
deBloisbanc [19]	1993	Yes	Yes	No	Yes	C, F, SA
Nelson [24]	1992	No	No	No	Yes	C, F, L, SA
Shapiro [25]	1992	No	No	No	No	Nil
Clemmer [18]	1990	Yes	Yes	No	No	Nil
Fink [21]	1990	Yes	No	Yes	Yes	C, F, SA, SC
Demarest [20]	1989	Yes	No	No	Yes	C, F, SA
Summer [26]	1989	No	Yes	No	Yes	C, F, L, SA
Gentilello [22]	1988	Yes	No	No	Yes	C, F, L, SA, SC

BC, blood culture; BQ, bronchoalveolar lavage with quantitative culture; C, persistent new changes on chest radiograph; F, fever; H, histologic evidence of pneumonia in lung tissue; L, leukocytosis or leukopaenia; PC, pleural fluid culture; SA, altered sputum appearance; SC, positive sputum culture.

ISSN: 1364-8535