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Figure 1 | Critical Care

Figure 1

From: Use of an integrated clinical trial database to evaluate the effect of timing of drotrecogin alfa (activated) treatment in severe sepsis

Figure 1

INDEPTH survival curves for placebo-receiving and DrotAA-treated patients by time to treatment. The percentage 28-day survivals are shown parenthetically in the key. Kaplan-Meier survival curves are displayed for therapy groups (namely DrotAA and placebo), as well as for time-to-treatment groups (namely 0 to 24 hours and more than 24 hours). Both DrotAA time-to-treatment curves were significantly different from the placebo time-to-treatment curves. At 14 days, the DrotAA earlier treatment curve (0 to 24 hours) started to diverge from the later treatment curve (more than 24 hours). The difference between the DrotAA earlier and later treatment curves was significant at 28 days (p = 0.03). DrotAA, drotrecogin alfa (activated).

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