Table 4 Diagnostic and severity criteria for sinusoidal obstruction syndrome
From: Clinical review: Specific aspects of acute renal failure in cancer patients
Diagnostic criteria | Hepatomegaly |
|---|---|
| Ā | Sudden weight gain (+ 2% of body weight) |
| Ā | Jaundice (total bilirubin >34 Ī¼mol/l) |
| Ā | Right upper quadrant pain |
| Ā | No other cause: |
| Ā | Budd-Chiari syndrome |
| Ā | Sepsis |
| Ā | Heart failure |
| Ā | Graft versus host disease |
Other symptoms | Cytolysis |
| Ā | Gall bladder wall thickening |
| Ā | Portal hypertension |
| Ā | Multiple organ failure |
| Ā | Thrombocytopenia |
Severe sinusoidal obstruction syndrome | Multiple organ failure |
| Ā | Thrombocytopenia |
| Ā | Cytolysis with ASAT or ALAT >750 IU/l |
| Ā | Confusion or disorientation |
| Ā | Maximum total bilirubin or severity of weight gain |