Figure 1
From: Macrophage migration inhibitory factor: controller of systemic inflammation
Scheme of macrophage migration inhibitory factor (MIF) induction of systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS) through the T-helper (TH)1/TH2 cell pathway. ACTH, adrenocorticotropic hormone; CPB, cardiopulmonary bypass; IL, interleukin.