Table 3 Univariate analysis: comparison of factors predicting intensive care mortality
From: Plasma DNA concentration as a predictor of mortality and sepsis in critically ill patients
Survived (n = 39) | Died (n = 13) | P value | |
|---|---|---|---|
Age (years) | |||
Median (interquartile range) | 70 (19) | 74 (11) | 0.49 |
Minimum–maximum | 16–85 | 36–81 | |
Male sex [n (%)] | 14 (36) | 6 (46) | 0.39 |
Operative reason for admission [n (%)] | 26 (67) | 7 (54) | 0.38 |
Admission Sepsis-related Organ Failure Assessment score | |||
Median (interquartile range) | 4 (5) | 8 (4) | 0.004 |
Minimum–maximum | 0–15 | 2–13 | |
Organ failures within the first 24 hours | |||
Cardiovascular failure [n (%)] | 11 (28) | 7 (54) | 0.11 |
Renal failure [n (%)] | 4 (10) | 4 (31) | 0.09 |
Respiratory failure [n (%)] | 25 (64) | 11 (85) | 0.30 |
Admission with sepsis [n (%)] | 12 (31) | 7 (54) | 0.19 |
Co-morbidities of patients prior to admission | |||
Chronic lung disease [n (%)] | 6 (15) | 1 (8) | 0.66 |
Ischaemic heart disease [n (%)] | 6 (15) | 5 (42) | 0.11 |
Diabetes mellitus [n (%)] | 5 (13) | 2 (17) | 0.99 |
Chronic renal failure [n (%)] | 1 (3) | 1 (8) | 0.44 |
Chronic liver failure [n (%)] | 0 (0) | 1 (8) | 0.25 |
Congestive cardiac failure [n (%)] | 3 (8) | 1 (8) | 0.99 |
Hypertension [n (%)] | 18 (46) | 5 (42) | 0.75 |
Plasma free DNA level (ng/ml) | |||
Median (interquartile range) | 71 (67) | 321 (189) | <0.001 |
Minimum–maximum | 8–1,622 | 40–8,849 |