Skip to main content
Figure 3 | Critical Care

Figure 3

From: A3 adenosine receptors and mitogen-activated protein kinases in lung injury following in vivo reperfusion

Figure 3

Western blot analyses of phospho-ERK1/2. (a) Representative Western blot and (b) densitometric analysis of five blots (mean ± standard error of the mean), expressed as a percentage of values for corresponding control-treated tissue samples (no ischemia or reperfusion). Groups: 1 = control, nonischemic group; 2 = ischemia/reperfusion; 3–5 = IB-MECA 50 μg/kg, 100 μg/kg, and 300 μg/kg, respectively, administered before reperfusion; 6 and 7 = MRS3558 50 μg/kg and 100 μg/kg, respectively, administered before reperfusion; 8 = MRS1191 pretreatment before MRS3558 (100 μg/kg) and beginning of reperfusion; and 9 = DMSO administration. Densitometry data presented is normalized to the intensity of actin bands. *P < 0.01 versus groups 1–4, 8, and 9. **P < 0.05 versus the other groups. DMSO, dimethyl sulfoxide; ERK, extracellular signal-regulated kinase.

Back to article page

Critical Care

ISSN: 1364-8535