The use of moderate hypothermia during cardiac surgery is associated with repression of tumour necrosis factor-α via inhibition of activating protein-1: an experimental study

Table 1 Oesophageal and myocardial temperatures before, during, and after CPB in pigs operated on under moderate hypothermia or normothermia

Time point	Esophageal temperature			Myocardial temperature
	Hypothermia (28°C)	Normothermia (37°C)	P	Hypothermia (28°C)	Normothermia (37°C)	P
Before CPB	35.9 ± 0.5	36.1 ± 0.9	NS	35.8 ± 0.6	35.7 ± 1.5	NS
10 minutes after institution of CPB	30.1 ± 4.4	36.7 ± 0.4	0.01	28.2 ± 0.4	36.4 ± 1.0	0.001
10 minutes after aortic cross clamping	28.1 ± 0.09	36.6 ± 0.6	0.001	17.2 ± 3.4	17.4 ± 2.4	NS
60 minutes after aortic cross clamping	33.3 ± 1.7	36.2 ± 0.3	0.05	28.1 ± 2.5	31.5 ± 1.5	NS
End of CPB	35.0 ± 1.9	36.6 ± 0.3	NS	34.8 ± 0.5	35.9 ± 1.0	NS
6 hours after CPB	36.1 ± 0.8	38.0 ± 0.5	0.005	36.4 ± 1.1	38.6 ± 0.6	NS

Results are expressed as mean ± standard deviation. CPB, cardiopulmonary bypass; NS, not significant.

ISSN: 1364-8535