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Table 2 Changes in components of the SIRS criteria for admissions with severe sepsis during the first 24 hours following admission to critical care, 1996 to 2004

From: The epidemiology of severe sepsis in England, Wales and Northern Ireland, 1996 to 2004: secondary analysis of a high quality clinical database, the ICNARC Case Mix Programme Database

 

Highest central temperaturea (°C)

Highest heart rate (min-1)

Highest non-ventilated respiratory rateb (min-1)

Lowest PaCO2 (kPa)

Mechanically ventilated, n (%)

Lowest white blood cell count (× 109l-1)

1996

38.2 (37.5–38.8)

127 (112–145)

28 (21–36)

4.5 (3.9–5.2)

2,733 (81.0)

11.1 (6.9–15.8)

1997

38.1 (37.5–38.8)

126 (112–144)

28 (22–36)

4.5 (3.9–5.2)

4,744 (79.0)

11.3 (6.9–16.1)

1998

38.1 (37.5–38.7)

125 (110–141)

28 (22–35)

4.5 (3.9–5.3)

6,893 (79.9)

11.3 (7.0–15.9)

1999

38.1 (37.5–38.8)

125 (110–140)

28 (22–36)

4.6 (3.9–5.3)

8,114 (79.1)

11.4 (7.1–16.1)

2000

38.0 (37.4–38.7)

125 (110–140)

28 (22–35)

4.6 (4.0–5.3)

8,624 (79.0)

11.5 (7.1–16.3)

2001

38.0 (37.4–38.7)

124 (110–140)

28 (22–35)

4.6 (4.0–5.4)

10,146 (76.3)

11.8 (7.4–16.6)

2002

38.0 (37.4–38.6)

122 (108–138)

28 (23–36)

4.6 (4.0–5.4)

11,904 (73.7)

11.8 (7.4–16.6)

2003

38.0 (37.4–38.6)

121 (108–138)

29 (23–36)

4.7 (4.0–5.4)

11,986 (73.1)

11.8 (7.3–16.8)

2004

38.0 (37.4–38.7)

120 (107–135)

29 (23–36)

4.6 (4.0–5.4)

5,141 (73.1)

11.9 (7.3–17.0)

Totalc

38.0 (37.4–38.7)

124 (110–140)

28 (22–36)

4.6 (4.0–5.4)

70,317 (76.4)

11.6 (7.2–16.5)

  1. Values are median (interquartile range) of the most extreme physiological measurement from the first 24 hours following admission to critical care, unless otherwise stated. aNon-central temperature +0.5°C used as a substitute for central temperature in admissions with no central temperature recorded. bFor admissions that were not mechanically ventilated for the entire of the first 24 hours following admission to critical care. cTotal includes 55 admissions from 1995 and 78 admissions from 2005. PaCO2, arterial carbon dioxide tension; SIRS, systemic inflammatory response syndrome.