Predicting late anemia in critical illness

Table 2 Risk factors for late transfusion or late anemia from multivariable models

Risk factor^a	Odds ratio (95% confidence interval)
	Late transfusion	Late anemia
Abnormal lactate (> 1.5 mg/dl)	1.64 (1.28–2.09)	1.79 (1.41–2.26)
Transfused	0.64 (0.45–0.87)	-
Surgical patient	2.51 (1.86–3.40)	2.90 (2.19–3.83)
Non-emergent surgery	1.72 (1.22–2.22)	1.60 (1.26–2.04)
Mechanical ventilation	1.73 (1.37–2.19)	-
Hemoglobin deficit^b	1.21 (1.16–1.26)	1.30 (1.25–1.35)
Abnormal creatinine (≥ 1.6 mg/dl)	1.75 (1.38–2.21)	-
Inotropic support	-	1.69 (1.29–2.21)

Late transfusion, transfused 7 days or more after admission to intensive care unit; late anemia, reached or would have reached 7.0 g/dl at 7 days or more after admission to intensive care unit. ^aWorst value recorded up to 6 hours after admission to intensive care unit. ^bCalculated as g/dl lower than 14 g/dl, with zero deficit defined as a baseline hemoglobin of at least 14 g/dl.

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