Skip to main content

Table 1 Gas exchange, respiratory system compliance and hemodynamics

From: Lung and 'end organ' injury due to mechanical ventilation in animals: comparison between the prone and supine positions

  Supine position Prone position P value 95% confidence interval of the difference
PO2/FIO2 (mmHg)
   Baseline 416 ± 23.6 412.4 ± 25.5 NS  
   90 minutes 105.6 ± 24.1 251.6 ± 56.1 <0.001 -208.9 to -83.0
   P value <0.0001 <0.004   
   95% confidence interval of the difference 272.8–247.9 84.8–236.7   
PCO2 (mmHg)
   Baseline 38.8 ± 1.8 40.8 ± 1.3 NS  
   90 minutes 57.2 ± 1.5 43.0 ± 1.2 <0.001 2.2 to 6.1
   P value <0.002 <0.04   
   95% confidence interval of the difference -5.0 to -6.9 -1.1 to -5.8   
pH
   Baseline 7.408 ± 0.013 7.398 ± 0.008 NS  
   90 minutes 7.322 ± 0.019 7.382 ± 0.018 0.0009 -0.08 to -0.03
   P value 0.0005 NS   
   95% confidence interval of the difference 0.063–0.108    
Static compliance of respiratory system (ml/cmH2O)
   Baseline 30.4 ± 3.8 25.9 ± 2.1 NS  
   90 minutes 18.2 ± 2.8 22.8 ± 2.3 <0.02 -8.3 to -0.86
   P value <0.001 <0.003   
   95% confidence interval of the difference -10.1 to -14.3 -1.7 to -4.5   
Blood pressure (mmHg)
   Baseline 81.80 ± 7.294 85.60 ± 9.476 NS  
   90 minutes 84.20 ± 5.167 86.00 ± 9.670 NS  
   P value NS NS   
   95% confidence interval of the difference     
Heart rate (beats/minutes)
   Baseline 117.2 ± 9.365 122.2 ± 6.140 NS  
   90 minutes 130.4 ± 4.722 132.8 ± 5.891 NS  
   P value 0.0074 0.0007   
   95% confidence interval of the difference -20.51 to -5.887 -13.72 to -7.484   
  1. Static compliance of respiratory system = (end inspiratory airway pressure – end-expiratory pressure)/tidal volume.