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Figure 1 | Critical Care

Figure 1

From: Systematic review of determinants of mortality in high frequency oscillatory ventilation in acute respiratory distress syndrome

Figure 1

Theoretical causal mechanism of the association between time on conventional mechanical ventilation (CV) prior to initiating high frequency oscillatory ventilation and mortality at 30 days. Conditioning by oxygenation index and age and APACHE II score would block the association if no unidentified intermediate causes or confounders were present. E, exposure; I, intermediate cause; C, confounders; Y, outcome.

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