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Table 2 Underlying diseases in intensive care unit patients with respiratory tract samples positive for Aspergillus spp.

From: Clinical relevance of Aspergillus isolation from respiratory tract samples in critically ill patients

Underlying condition Associated with invasive aspergillosisa Associated with Aspergillus colonisation
Hematological malignancyb 28 (2) 3
   With neutropenia 6 (1) 1
   Post bone marrow/stem cell transplantation 2 0
Myelodysplastic syndrome 4 -
Solid tumor with chemotherapy 3 1
Solid tumor without chemotherapy 5 3
Graves' disease - 1
Immunosuppressive therapy 14 (4) 8
   Solid organ transplant 8 (2) 4
   Auto-immune disease 4 (2) 4
   Lung fibrosis 2 0
Aplastic anemia 1 1
Chronic obstructive pulmonary disease 29 (4) 25
   Requiring chronic systemic corticosteroid use 21 (3) 12
   Requiring inhalation corticosteroids 24 (3) 16
Asthma 2 1
Liver cirrhosis 3 (2) 2
Malnutrition 3 -
Diabetes mellitus 8 (1) 9
Alcoholism 5 (2) 3
Chronic heart failure 6 5
Chronic renal failure – dialysis dependent 3 (1) 2
Lung fibrosis 2 1
Active Cytomegalovirus disease 3 1
Active tuberculosis - 1
Absence of known underlying disease 14 (5) 27
  1. aNumbers in parentheses indicate cases with definite invasive aspergillosis. bP value < 0.05 for difference between patients with invasive aspergillosis (definite + probable) and colonisation.