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Table 1

From: Efficacy of recombinant activated factor VII in the management of severe hemorrhage following cardiac surgery

Variable

Before rFVIIa

30 min later

3 hours later

Prothrombin time (s)

38.4 ± 3.7

18.0 ± 1.8*

19.4 ± 1.7*

Thrombin time (s)

12.9 ± 1.3

14.4 ± 1.9

11.0 ± 0.5

APTT (s)

51.3 ± 2.9

44.9 ± 3.9

43.7 ± 3.1

ACT (s)

105.4 ± 4.2

95.9 ± 4.9

97.9 ± 5.8

Platelet count

126.9 ± 15.1

139.2 ± 19.1

142.4 ± 13.3

Platelet agg (%)

27.6 ± 5.4

38.8 ± 5.4

53.3 ± 6.5*

Clot time (min)

11.8 ± 0.9

9.3 ± 1.1

10.8 ± 1.6

  1. *P < 0.05 vs before rFVIIa.