Cardiorespiratory effects of inhaled nitric oxide during acute hypercapnia with and without correction of blood pH in a acute respiratory failure in piglets

Table 1 Table1

	BL	NC	HC-I	HC-Ic	HC-II	HC-IIc
PAP (torr)NO-0	21.8 ± 1.4	28.1 ± 0.6	32 ± 1.7	29.2 ± 1.2	35.1 ± 1.8	30.8 ± 1.6#
PAP(torr)NO-10	19 ± 1.1	25.8 ± 1.2	27 ± 3^**	26 ± 1	28.5 ± 1.1^**	26.3 ± 1.3^*
MAP (torr)NO-0	83 ± 1.7	79.3 ± 2.9	72.6 ± 2.5	78.4 ± 3.7	74.2 ± 3.0	76.7 ± 4.1
MAP(torr)NO-10	82 ± 1.8	81 ± 2.4	79 ± 3.8	82 ± 5	74 ± 4	77 ± 4
CO (l/min)NO-0	2.6 ± 0.39	1.9 ± 0.19	1.72 ± 0.15	1.77 ± 0.1	1.90 ± 0.17	1.90 ± 0.2
CO(l/min)NO-10.	2.5 ± 0.4	2.0 ± 0.2	1.77 ± 0.11	1.72 ± 0.14	1.91 ± 0.16	2.16 ± 0.21
PVR (dyne.s.cm^-5)NO-O	362 ± 53	684 ± 85	928 ± 157	694 ± 97	956 ± 142	823 ± 197
PVR (dyne.s.cm^-5)NO-10	275 ± 41	582 ± 99	642 ± 69^*	611 ± 123	685 ± 124^*	469 ± 107^*
PaO₂/FiO₂ (torr)NO-0	454 ± 37	98 ± 12	101 ± 5.2	109 ± 12	95 ± 5	106 ± 13
PaO₂/FiO₂ (torr)NO-10	469 ± 35	148 ± 11^**	151 ± 13^**	146 ± 17^*	154 ± 25^**	148 ± 21^*

^* P < 0.05 vs iNO 10ppm, ^** P < 0.01 vs iNO 10ppm, #P < 0.05 vs pH-correction, BL, baseline; NC, normocapnia; HC-I, hypercapnia 65 torr: HC-II, hypercapnia 85 torr; C, pH-correction

ISSN: 1364-8535