Table 3 Mean (FNO), inspiratory (FINO) and expiratory (FENO) intratracheal NO concentrations, mean NO₂ intratracheal concentrations and methemoglobin (MetHb) blood levels measured in 16 patients with ARDS receiving increasing concentrations of inhaled NO at FiO₂ 0.85

0.15

0.45

1.5

4.5

15

45

150

0.102 ± 0.004

0.32 ± 0.011

1.05 ± 0.02

2.98 ± 0.06

10.4 ± 0.2

26 ± 0.8

100 ± 4

0.15 ± 0.006

0.45 ± 0.073

1.5 ± 0.2

4.5 ± 0.3

15.3 ± 1.2

45.2 ± 0.9

nd

0.004 ± 0.0005

0.1 ± 0.02

0.6 ± 0.05

1.95 ± 0.1

6 ± 0.2

17 ± 0.9

nd

0.02 ± 0.004

0.03 ± 0.01

0.03 ± 0.01

0.06 ± 0.02

0.3 ± 0.1

0.8 ± 0.3

4 ± 0.9

0.9 ± 0.1

1 ± 0.1

0.9 ± 0.1

0.9 ± 0.1

1 ± 0.1

1.4 ± 0.2

3.8 ± 0.5