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Table 2 Initial hemodynamic and respiratory characteristics of the 16 patients: intermittent positive pressure ventilation, ZEEP and FiO2= 1.0

From: Inhaled nitric oxide in acute respiratory distress syndrome with and without septic shock requiring norepinephrine administration: a dose–response study

  Patients without septic shock
  1 2 3 4 5 6 7 8 Mean ± SEM
PaCO2 (mmHg) 66 45 41 41 46 49 58 56 50 ± 3
VDA/VT (%) 39 26 26 35 18 45 46 33 34 ± 4
PaO2 (mmHg) 58 107 111 104 81 49 188 64 95 ± 16
QVA/QT (%) 53 43 34 29 46 71 36 53 46 ± 5
Cqs (ml/cmH2O) 44 57 52 50 36 25 57 - 46 ± 4
Crs (ml/cmH2O) 50 56 55 82 29 19 84 58 54 ± 8
MPAP (mmHg) 21 31 20 43 27 28 19 36 28 ± 3
PVRI (dyn s/cm5m2) 168 265 443 1329 298 215 246 286 406 ± 135
PCWP (mmHg) 4 11 6 3 7 2 7 10 6 ± 1
CI (l/min/m2) 8.3 6.1 2.6 2.4 5.3 9.7 3.9 7.2 5.7 ± 1
  Patients with septic shock
  9 10 11 12 13 14 15 16 Mean ± SEM
PaCO2 (mmHg) 55 56 56 57 39 44 33 50 48 ± 3
VDA/VT (%) 48 38 33 42 33 23 25 39 35 ± 3
PaO2 (mmHg) 130 68 59 57 145 106 88 77 88 ± 11
QVA/QT (%) 50 53 50 51 36 43 41 40 47 ± 2
Cqs (ml/cmH2O) 43 58 30 26 83 52 39 59 49 ± 6
Crs (ml/cmH2O) 50 56 48 39 77 57 57 59 56 ± 4
MPAP (mmHg) 24 37 45 31 21 39 27 27 32 ± 3
PVRI (dyn s/cm5m2) 399 590 489 377 360 471 321 652 442 ± 40
PWP (mmHg) 4 14 13 5 10 9 14 4 9 ± 1
CI (l/min/m2) 3.9 3.1 5.3 5.4 2.4 5.1 3.3 2.9 4.3 ± 1
  1. VDA/VT = alveolar dead space; QVA/QT = venous admixture; Cqs = quasi-static respiratory compliance; Crs = respiratory compliance (slope of the P-V curve above the lower inflection point); MPAP = mean pulmonary arterial pressure; PVRI = pulmonary vascular resistance index; PCWP = pulmonary capillary wedge pressure; CI = cardiac index.