Table 3 Evolution of hemodynamic variables and catecholamine infusion rates after terlipressin therapy
From: Rescue treatment with terlipressin in children with refractory septic shock: a clinical study
Before terlipressin therapy | Time after terlipressin therapy | ||||||
|---|---|---|---|---|---|---|---|
30 min | 60 min | 4 hours | 12 hours | 24 hours | 48 hours | ||
Systolic blood pressure (mmHg) | 77 (50–140) | 108 (61–154)* | 102.5 (61–137)* | 99 (65–147) | 91 (70–120) | 107 (55–118) | 105 (65–130) |
Mean blood pressure (mmHg) | 50.5 (37–93) | 77 (42–100)** | 69.5 (41–104)* | 74 (40–95) | 62 (40–90) | 68 (35–90) | 73 (40–103) |
Diastolic blood pressure (mmHg) | 38 (25–70) | 57 (32–72)* | 55.5 (31–90)* | 48 (25–86) | 50 (20–80) | 48 (26–77) | 53 (30–90) |
Heart rate (beats/min) | 155 (80–205) | 149 (114–186) | 148 (85–190) | 148 (110–190) | 146 (114–185) | 142 (102–170) | 148 (101–170) |
Central venous pressure (mmHg) | 14 (4–23) | 13 (3–23) | 12.5 (3–17) | 13 (3–27) | 12 (4–24) | 12 (5–18) | 13.6 (5–22) |
Catecholamines (µg/kg/min) | |||||||
Noradrenaline | 2 (1–4) | 1 (0–3) | 1.15 (0–3) | 1.4 (0–2) | 1 (0–2.6)* | 1 (0–2.5)** | 0.1 (0–1)** |
Adrenaline | 1.2 (0.4–4) | 1 (0.5–6) | 1 (0.3–4) | 0.7 (0.2–3) | 0.6 (0.1–2) | 1 (0.2–2) | 0.5 (0–2.5) |
Dopamine | 21.5 (10–52) | 16.3 (3–40) | 17.5 (0–52) | 10 (0–40) | 15.8 (0–40) | 20 (3–40) | 11.6 (0–45) |
Dobutamine | 22.5 (5–40) | 20 (0–40) | 20 (0–40) | 20 (0–40) | 20 (0–40) | 20 (0–40) | 22.5 (10–30) |
Inotropic equivalenta | 176 (141–552) | 153.5 (67–460) | 128.5 (57–340) | 117.5 (20–340)* | 82 (0–371)** | ||