Figure 2
From: Study protocol: The Improving Care of Acute Lung Injury Patients (ICAP) study
Power to detect a difference in physical functioning domain at 2 years in ALI survivors. Compares the projected power of the Improving Care of ALI Patients (ICAP) study with that of a hypothetical cohort study with a sample size of 80 acute lung injury/acute respiratory distress syndrome (ALI/ARDS) survivors [16], assuming a standard deviation of 29 points in the SF-36 physical functioning quality of life domain [8], 50% mortality in the ICAP study patient group receiving more frequent lower tidal volume ventilation (LTVV), a relative hazard of 0.7 for mortality comparing higher with lower frequency of LTVV, 10% additional losses to follow-up in both ICAP patient groups, and a two-sided type I error (α) of 0.05. ALI, acute lung injury.