Parameter (cutoff value) | Predicted risk | ||||
---|---|---|---|---|---|
 | Outcome | Infection | Sepsis/severe sepsis/septic shock | SOFA score ≥12 within 21 days | ICU stay >7 days |
 | AUC (odds ratio, 95% CI) (P < 0.002), chi-square test | Sensitivity/specificity (cutoff value) | AUC (odds ratio, 95% CI) (P < 0.001) | Sensitivity/specificity (cutoff value) | AUC (odds ratio, 95% CI) (P < 0.002) |
Initial procalcitonin (≥1 ng/ml) | 0.732 (-, not increased) | 93%/41% (0.62 ng/ml) | 0.805 (6.1, 2.5–15.7) | 90%/48% (0.53 ng/ml) | 0.798 (7.8, 2.8–21.9) |
 |  | 80%/59% (1.31 ng/ml) |  | 80%/64% (0.97 ng/ml) |  |
 |  | 73%/60% (1.37 ng/ml) |  | 70%/74% (1.36 ng/ml) |  |
Initial C-reactive protein (>100 mg/l) | 0.564 (-, not increased) | 87%/37% (105 mg/l) | 0.674 (-, not increased) | 90%/30% (76 mg/l) | 0.639 (-, not increased) |
 |  | 80%/41% (111 mg/l) |  | 80%/64% (104 mg/l) |  |
 |  | 73%/45% (122 mg/l) |  | 70%/52% (121 mg/l) |  |
Injury Severity Score (≥20) | 0.869 (1.3, 1.1–1.6) | 100%/61% (26.0) | 0.760 (10.6, 3.3–34.1) | 90%/54% (20.0) | 0.721 (7.0, 2.2–22.4) |
 |  | 80%/77% (31.5) |  | 88%/54% (21.5) |  |
 |  | 73%/80% (34.0) |  | 73%/70% (26.0) |  |
Initial SOFA score (≥12) | 0.864 (11.6, 3.3–40.6) | 87%/68% (10.5) | 0.805 (6.0, 2.0–18.4) | 95%/42% (7.5) | 0.788 (4.9, 1.7–13.9) |
 |  | 73%/76% (11.5) |  | 82%/70% (9.5) |  |
 |  | 67%/85% (12.5) |  | 65%/78% (10.5) |  |
APACHE II score (≥20) | 0.783 (13.1, 3.5–48.9) | 93%/39% (13.5) | 0.685 (-, not increased) | 90%/40% (12.5) | 0.678 (-, not increased) |
 |  | 87%/48% (14.5) |  | 82%/46% (13.5) |  |
 |  | 73%/61% (15.5) |  | 57%/66% (15.5) |  |