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Table 2 Characteristics of the study group

From: Is albumin administration in the acutely ill associated with increased mortality? Results of the SOAP study

 

All patients (n = 3,147)

Stratifying according to albumin administration

  

Albumin (n = 354)

No albumin (n = 2,793)

p value

Age, mean ± SDa

61 ± 17

62 ± 15

60 ± 18

0.15

Male (%)b

1,920 (61.7%)

219 (62.4)

1,701 (61.6)

0.776

Chronic diseases (%)

    

   COPD

340 (10.8)

38 (10.7)

302 (10.8)

0.964

   Cancer

415 (13.2)

66 (18.7)

349 (12.5)

<0.001

   Heart failure

307 (9.8)

42 (11.9)

265 (9.5)

0.156

   Diabetes

226 (7.2)

29 (8.2)

197 (7.1)

0.434

   Liver cirrhosis

121 (3.8)

32 (9.0)

89 (3.2)

<0.001

   Hematologic cancer

69 (2.2)

13 (3.7)

56 (2.0)

0.053

   HIV/AIDS

26 (0.9)

6 (1.7)

20 (0.7)

0.18

Surgical admission (%)

1,388 (44.1)

218 (61.6)

1,170 (41.9)

<0.001

SAPS II score, mean ± SD

36.5 ± 17.1

41.5 ± 17.3

35.9 ± 17.0

<0.001

Admission SOFA score, mean ± SD

5.1 ± 3.8

6.9 ± 3.9

4.9 ± 3.8

<0.001

Infection (%)

1,177 (37.4)

225 (63.6)

952 (34.1)

<0.001

   On admission

777 (24.7)

140 (39.5)

637 (22.8)

<0.001

Severe sepsis (%)

930 (29.6)

202 (57.1)

728 (26.1)

<0.001

   On admission

552 (17.5)

112 (31.6)

440 (15.8)

<0.001

Septic shock (%)

462 (16.5)

144 (40.7)

318 (11.4)

<0.001

   On admission

243 (7.7)

62 (17.5)

181 (6.5)

<0.001

ICU stay, median (IQ)

3.0 (1.7–6.9)

8.0 (3.1–17.8)

2.9 (1.6–6)

<0.001

Hospital stay, median (IQ)c

15 (7–32)

27 (12–49)

14 (7–29)

<0.001

ICU mortality (%)d

583 (18.5)

125 (35.3)

458 (16.4)

<0.001

Hospital mortality (%)c

747 (23.7)

147 (41.5)

600 (21.3)

<0.001

  1. aNine missing. bThirty-five missing. cThirty-nine missing. dOne missing. ICU, intensive care unit; IQ, interquartile range; SAPS, simplified acute physiology score; SD, standard deviation; SOFA, sequential organ failure assessment.