Is albumin administration in the acutely ill associated with increased mortality? Results of the SOAP study

Table 1 Propensity score model

	Coefficient	SEM	Wald	Odds ratio (95% CI)	p value
SOFA score^a	0.078	0.016	22.78	1.08 (1.05–1.12)	<0.001
HES administration^b	0.591	0.129	21.10	1.81 (1.40–2.32)	<0.001
RBC transfusion^b	1.296	0.134	93.03	3.65 (2.81–4.76)	<0.001
Cirrhosis	0.796	0.239	11.10	2.22 (1.39–3.54)	0.001
Medical admission	-0.407	0.132	9.47	0.67 (0.51–0.86)	0.002
Cancer	0.451	0.167	7.32	1.57 (1.13–2.18)	0.007
Sepsis^a	0.332	0.133	6.24	1.39 (1.074–1.81)	0.012
Hemofiltration^a	0.380	0.292	1.69	1.46 (0.83–2.59)	0.193
Hemodialysis^a	0.525	0.368	2.04	1.69 (0.82–3.48)	0.154
Constant	-0.591	0.543	1.19	NA	0.276

The basic model used to determine the propensity score was a multivariable, forward stepwise, logistic regression analysis with albumin administration as the dependent factor. ^aOn the day of onset of albumin administration in the albumin group and on admission in other patients. ^bAt any time during intensive care unit stay. CI, confidence interval; HES, hydroxyethyl starch; RBC, red blood cell; SEM, standard error of mean; SOFA, sequential organ failure assessment.

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