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Table 3 Blood gas analysis and haemodynamic parameters at the end of the 6-hour observational period

From: Early veno-venous haemodiafiltration for sepsis-related multiple organ failure

Parameter Group 1 (n = 40) Group 2 (n = 20) P value
PaO2/FiO2 (mmHg) 139 ± 68 100 ± 68 0.046*
PaCO2 (mmHg) 49 ± 11 53 ± 12 0.18
BE (mmol/l) -11 ± 4 -13 ± 5 0.10
pH 7.17 ± 0.11 7.11 ± 0.13 0.06
Lactate (mmol/l) 4.3 ± 1.8 5.8 ± 3.2 0.020*
HR (beats/minute) 118 ± 20 113 ± 20 0.48
CI (l/minute per m2) 3.2 ± 1.2 2.9 ± 1 0.39
LVEF (%) 50 ± 16 48 ± 19 0.73
Vasopressor support (choice; n [%])
   Noradrenaline 19 (48%) 9 (45%) 0.97
   Noradrenaline + dobutamine 7 (18%) 4 (20%)  
   Adrenaline 14 (35%) 7 (35%)  
Vasopressor support (dosage; μg/kg per minute) 1.1 ± 0.8 2.3 ± 1.4 0.002*
  1. Shown is a comparison of blood gas analysis and haemodynamic parameters at the end of the 6-hour observational period between group 1 (responders) and group 2 (nonresponders). Vasopressor dosage is the cumulative dosage of major catecholamines (noradrenaline [norepinephrine] or adrenaline [epinephrine]), with dobutamine being given at 5 μg/kg per minute. *Statistically significant finding. BE, base excess; CI, cardiac index; FiO2, fractional inspired oxygen; HR, heart rate; LVEF, left ventricular ejection fraction; PaCO2, arterial carbon dioxide tension; PaO2, arterial oxygen tension.