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Table 1 Risk of sARF associated with selected co-morbidities among adult residents of the Calgary Health Region, Canada

From: Prognosis for long-term survival and renal recovery in critically ill patients with severe acute renal failure: a population-based study

Underlying condition Number of patients with sARF (n = 240) Estimated number with underlying condition at risk in CHR Annual incidence (per 100,000 population) Relative riska (Exact 95% CI)
Heart disease 120 85,576 140 24.0 (18.5–31.2)b
Stroke 44 21,394 206 22.0 (15.6–31.0)b
Chronic pulmonary disease 83 68,461 121 16.0 (12.1–21.0)b
Diabetes mellitus 72 85,576 84 10.3 (7.7–13.6)b
Cancer 38 42,788 89 9.2 (6.3–13.1)b
Connective tissue disease 12 21,394 56 5.2 (2.7–9.3)b
Chronic kidney disease 45 96,273 47 4.9 (3.5–6.8)b
Alcohol abuse 57 145,480 39 4.3 (3.1–5.8)b
  1. aRelative risk calculated by ((Number of sARF patients with underlying condition/Number at-risk with underlying condition in CHR)/(Number of sARF patients without underlying condition/Number at-risk without underlying condition in CHR)). bp value < 0.0001 for each underlying condition relative risk. Underlying conditions were defined by using the Charlson Co-morbidity Index [25]. The presence of alcohol abuse was defined by documentation in patient medical record or by history. CHR, Calgary Health Region; CI, confidence interval; sARF, severe acute renal failure.