|
Underlying condition
|
Number of patients with sARF (n = 240)
|
Estimated number with underlying condition at risk in CHR
|
Annual incidence (per 100,000 population)
|
Relative riska (Exact 95% CI)
|
|---|
|
Heart disease
|
120
|
85,576
|
140
|
24.0 (18.5–31.2)b
|
|
Stroke
|
44
|
21,394
|
206
|
22.0 (15.6–31.0)b
|
|
Chronic pulmonary disease
|
83
|
68,461
|
121
|
16.0 (12.1–21.0)b
|
|
Diabetes mellitus
|
72
|
85,576
|
84
|
10.3 (7.7–13.6)b
|
|
Cancer
|
38
|
42,788
|
89
|
9.2 (6.3–13.1)b
|
|
Connective tissue disease
|
12
|
21,394
|
56
|
5.2 (2.7–9.3)b
|
|
Chronic kidney disease
|
45
|
96,273
|
47
|
4.9 (3.5–6.8)b
|
|
Alcohol abuse
|
57
|
145,480
|
39
|
4.3 (3.1–5.8)b
|
- aRelative risk calculated by ((Number of sARF patients with underlying condition/Number at-risk with underlying condition in CHR)/(Number of sARF patients without underlying condition/Number at-risk without underlying condition in CHR)). bp value < 0.0001 for each underlying condition relative risk. Underlying conditions were defined by using the Charlson Co-morbidity Index [25]. The presence of alcohol abuse was defined by documentation in patient medical record or by history. CHR, Calgary Health Region; CI, confidence interval; sARF, severe acute renal failure.
