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Table 3 Tissue perfusion parameters in baboons infused with live Escherichia coli and treated with placebo or anti-L-selectin antibody

From: Anti-L-selectin antibody therapy does not worsen the postseptic course in a baboon model

  Time (hours)
  -0.5 0 1 2 4 6 10 24 32 48 72
aBE (mEQ/l)            
   Placebo 2.7 ± 0.5 4.0 ± 0.6 2.4 ± 0.3 0.8 ± 0.4 -0.4 ± 0.5 -0.4 ± 0.5 -3.4 ± 0.9 -6.6 ± 0.9 -2.6 ± 1.3 3.1 ± 2.6 7.9 ± 0.6
   L-SEL-Ab 4.0 ± 0.9 4.3 ± 0.9 3.1 ± 0.9 0.5 ± 1.0 -0.7 ± 1.2 -0.8 ± 1.0 -5.3 ± 1.7 -10.1 ± 2.6 -4.8 ± 2.8 2.2 ± 2.5 7.3 ± 2.1
Lactate (mmol/l)            
   Placebo 3.4 ± 0.8 3.3 ± 0.8 2.4 ± 0.4 3.5 ± 0.4 5.2 ± 0.4 4.9 ± 0.4 7.3 ± 0.7 12.1 ± 1.0 7.8 ± 0.8 6.7 ± 0.8 5.2 ± 0.6
   L-SEL-Ab 3.9 ± 0.9 3.9 ± 0.9 1.9 ± 0.2 4.3 ± 0.7 6.1 ± 0.9 6.1 ± 0.7 9.2 ± 1.4 14.5 ± 1.9 9.8 ± 1.0 6.7 ± 0.8 6.7 ± 1.1
  1. aBE, arterial base excess; L-SEL-Ab, anti-L-selectin antibody.