Skip to main content

Table 1 TNF-α and IL-6 in baboons infused with live Escherichia coli and treated with placebo or anti-L-selectin antibody

From: Anti-L-selectin antibody therapy does not worsen the postseptic course in a baboon model

  Time (hours)
  -0.5 0 1 2 4 6 10 24 32 48 72
TNF-α (pg/ml)            
   Placebo 0 ± 0 2 ± 2 5,950 ± 1,762 6,325 ± 2,026 244 ± 71 55 ± 18 28 ± 15 21 ± 7 19 ± 7 8 ± 5 0 ± 0
   L-SEL-Ab 6 ± 4 1 ± 1 9,048 ± 2,227 6,648 ± 1,465 236 ± 45 60 ± 9 39 ± 7 33 ± 11 34 ± 11 37 ± 15 39 ± 15
IL-6 (pg/ml)            
   Placebo 4 ± 3 17 ± 8 2,059 ± 263 6,968 ± 718 7,331 ± 963 6,082 ± 832 5,364 ± 773 3,032 ± 900 1,921 ± 860 2,435 ± 1,635 896 ± 73
   L-SEL-Ab 13 ± 5 6 ± 4 2,270 ± 665 7,392 ± 802 7,490 ± 773 7,075 ± 765 5,952 ± 500 3,547 ± 644 2,550 ± 689 1,684 ± 761 907 ± 77
  1. IL-6, interleukin-6; L-SEL-Ab, anti-L-selectin antibody; TNF-α, tumor necrosis factor-α.