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Table 2 Outcomes measured in a randomized controlled trial of recombinant activated factor VII

From: Recombinant activated factor VIIa and hemostasis in critical care: a focus on trauma

 

Blunt trauma

Penetrating trauma

Outcomes

rFVIIa

Placebo

P

rFVIIa

Placebo

P

Mortality

25%

30%

0.58

24%

28%

0.69

MOF/ARDS

10%

23%

0.07

7%

17%

0.11

ICU-free days

13

8

0.18

24

20

0.26

Ventilation-free days

17

14

0.44

26

22

0.17

  1. Both intensive care unit (ICU)-free and ventilator-free days were measured for 30 days. ARDS, acute respiratory distress syndrome; MOF, multiple organ failure; rFVIIa, activated recombinant factor VII.