Table 2 Time course of heart rate, MAP, ICP and the CPP for the two different treatment groups
Start infusion | Terminating infusion | +10 min | +30 min | +60 min | |
|---|---|---|---|---|---|
Heart rate, l/min | |||||
7.2% NaCl/HES 200/0.5 | 76 [52–92] | 78 [60–104] | 77 [62–107] | 78 [62–101] | 79 [61–99] |
Mannitol 15% | 78 [58–95] | 80 [58–96] | 80 [60–95] | 81 [58–93] | 79 [56–96] |
MAP, mmHg | |||||
7.2% NaCl/HES 200/0.5 | 84 [64–98] | 84* [68–96] | 84* [67–97] | 85* [74–100] | 84 [63–94] |
Mannitol 15% | 84 [68–92] | 85 [65–98] | 83 [69–105] | 81 [69–106] | 82 [68–108] |
ICP, mmHg | |||||
7.2% NaCl/HES 200/0.5 | 22 [19–31] | 15** [8–18] | 12** [2–16] | 10**,++ [6–14] | 11**,+ [5–18] |
Mannitol 15% | 23 [19–30] | 14** [7–20] | 13** [4–19] | 12** [6–19] | 14** [7–20] |
CPP, mmHg | |||||
7.2% NaCl/HES 200/0.5 | 60 [39–78] | 72** [54–85] | 72** [55–89] | 75**, #[62–86] | 73**, #[58–88] |
Mannitol 15% | 61 [47–71] | 70** [50–79] | 70** [56–92] | 72** [60–93] | 69** [56–89] |