Table 1 Patient characteristics at study entry
HFOV | CV | |
|---|---|---|
N | 37 | 24 |
Female:male ratio | 9/28 (24%) | 10/14 (42%) |
Mean age (years) | 81.0 ± 20.5 | 81.7 ± 12.5 |
Weight | 50.7 ± 17.4 | 55.4 ± 12.8 |
APACHE II score | 21.1 ± 7.6 | 20.1 ± 9.3 |
Diagnosis (%) | ||
Trauma | 1 (3) | 2 (9) |
Sepsis | 25 (68) | 13 (57) |
Pneumonia | 8 (22) | 3 (13) |
Other | 3 (8) | 5 (22) |
Site (%) | ||
United Kingdom | 24 (65) | 15 (63) |
France | 5 (21) | 7 (19) |
Germany | 4 (17) | 6 (16.2) |
Ventilation time prior to study (days) | 2.1 ± 2.6 | 1.5 ± 1.8 |
Oxygenation index | 25.2 ± 13.0 | 18.0 ± 7.4 |
Ventilatory index | 33.8 ± 20.4 | 30.3 ± 12.5 |
Respiratory rate (per min) | 18.1 ± 4.1 | 17.8 ± 4.6 |
Tidal volume(ml) | 618.4 ± 142.6 | 549.7 ± 130 |
Tidal volume per ideal bodyweight (ml/kg) | 9.3 ± 2.2 | 8.4 ± 2.0 |
Peak inspiratory pressure (cmH2O) | 33.1 ± 6.8 | 32.3 ± 5.4 |
Positive end-expiratory pressure (cmH2O) | 13.9 ± 3.8 | 12.9 ± 3.2 |
Mean airway pressure (cmH2O) | 21.5 ± 5.4 | 21.0 ± 5.1 |
FiO2 | 0.84 ± 0.19 | 0.76 ± 0.19 |
pH | 7.3 ± 0.13 | 7.3 ± 0.11 |
paCO2 (mmHg) | 53.5 ± 17.3 | 52.2 ± 11.9 |
paO2 (mmHg) | 80.8 ± 24.1 | 93.3 ± 24.5 |
SaO2 (percentage) | 90.8 ± 6.4 | 94.3 ± 3.1 |
Heart rate | 109.8 ± 23.7 | 111.2 ± 29.5 |
Mean arterial pressure (cmH2O) | 75.3 ± 13.1 | 72.2 ± 14.1 |
Central venous pressure (cmH2O) | 13.5 ± 4.2 | 13.8 ± 4.9 |