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Table 1 Characteristics of COPD patients assigned to receive intrapulmonary percussive ventilation or standard treatment at inclusion

From: Intrapulmonary percussive ventilation in acute exacerbations of COPD patients with mild respiratory acidosis: a randomized controlled trial [ISRCTN17802078]

 

IPV (n = 16)

Standard treatment (n = 17)

p-value

Age (years)

69.2 ± 6.0

70.2 ± 5.0

NS

SAPS II

25.4 ± 6.0

25.4 ± 4.0

NS

Hb (g/dl)

13.7 ± 1.3

14.0 ± 1.4

NS

HR (beats/min)

117 ± 16

115 ± 19

NS

RR (breaths/min)

36 ± 2

36 ± 3

NS

SBP (mmHg)

141 ± 15

143 ± 16

NS

pH

7.37 ± 0.01

7.37 ± 0.01

NS

PaCO2 (Torr)

57.6 ± 4.5

58.0 ± 3.0

NS

PaO2 (Torr)a

56.9 ± 3.0

56.7 ± 3.0

NS

Bicarbonate (mmol/l)

33 ± 3

33 ± 3

NS

FEV1 (%)b

39 ± 7

38 ± 8

NS

  1. aPatients received oxygen with nasal cannulae to maintain a target oxygen saturation (recorded by pulse oximetry) of 88% to 92%. Mean oxygen flow was 2.0 ± 0.5 l/min and 2.0 ± 0.5 l/min in the IPV group and the control group, respectively (p = NS).
  2. bFEV1 was obtained from previous spirometric tests in 13 patients in the IPV group and in 14 patients in the control group (the last test was retained). For the other patients (three in the IPV group and three in the control group), reliable pulmonary function data were obtained within two months of inclusion. FEV1, forced expiratory volume in one second; Hb, hemoglobin; HR, heart rate; IPV, intrapulmonary percussive ventilation; RR, respiratory rate; SAPS II, simplified acute physiologic score; SBP, systolic arterial blood pressure; NS, not statistically significant.