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Table 2 Predisposing factors and signs of severity

From: Severe community-acquired meningitis

Aetiologic agent

Streptococcus pneumoniae

Predisposing factors

Neisseria meningitidis

Streptococcus pneumoniae

Neisseria meningitidis

Previous history of head injury, surgery at the base of the skull, meningitis, rhinorrhea, sudden onset, neurological signs, otitis, sinusitis or associated pneumopathy, asplenia, human immunodeficiency virus infection

Neisseria meningitidis

Neisseria meningitidis

Neisseria meningitidis

Possible epidemic, purpura

Neisseria meningitidis

Listeria monocytogenes

Absence of predisposing factors and signs of severity

Immunodepression, signs of rhomboencephalitis, cloudy cerebrospinal fluid with mixed composition

Neisseria meningitidis

Haemophilus influenzae

Listeria monocytogenes

Age <5 years, absence of vaccination.

Suggestive features and comments

Principal signs of severity

Suggestive features and comments

Purpura fulminans, deep coma (Glasgow coma score <8), cardiorespiratory failure

Aetiologic diagnoses and suggestive features