From: Factors that predict outcome of intensive care treatment in very elderly patients: a review
Study | Sample | Study type | Age | Main findings |
---|---|---|---|---|
Chelluri et al. (1993) [10] | 97 ICU patients | Prospective chart investigation | 65–74 years (n = 43) and ≥75 years (n = 54) | Age itself was not an adequate predictor of long-term survival and quality of life, but severity of illness was |
Dardaine et al. (1995) [7] | 110 ICU patients on mechanical ventilation | Prospective cohort study | > 70 years | ICU mortality was 31% and 6-month mortality was 52%; outcome predictors were shock on admission and previous health status |
Cohen and Lambrinos (1995) [8] | 14,848 ICU patients on mechanical ventilation | Retrospective cohort study | >18 years | In-hospital mortality, in patients receiving mechanical ventilation aged ≥85 years, was 70% versus 32% in patients aged ≤29 years |
Dewar et al. (1999) [9] | 37,573 patients on prolonged mechanical ventilation | Retrospective database analysis | > 18 years | Inverse relation between age and survival; older survivors were often discharged to residential health care facilities |
Ely et al. (1999) [12] | 300 ICU patients | Prospective cohort study | <75 years versus >75 years | No difference in duration of artificial ventilation |
Montuclard et al. (2000) [13] | 75 ICU patients | Prospective cohort study | > 70 years | ICU mortality was 60% in elderly patients receiving ICU treatment |
Ely et al. (2002) [14] | 902 Patients with acute lung injury or ARDS | Prospective cohort study | <70 years (n = 729) and >70 years (n = 173) | Patients aged 70 years and older were twice as likely to die than were younger patients, and had greater difficulty achieving liberation from the ventilator |
Rosenthal et al. (2002) [15] | 156,136 Consecutive admissions to medical, surgical, neurological, and mixed medical/surgical ICUs | Retrospective cohort study | 18–100 years | The adjusted odds of death increased with each 5-year age increment |
Djaiani and Ridley (1997) [17] | 474 ICU patients | Prospective cohort study | >70 years | The 1-year survival of patients aged <85 years was 56%, which was significantly better than that of patients aged >85 years (27%) |
Bo et al. (2003) [16] | 659 Medical ICU patients | Prospective cohort study | ≥ 65 years | Independent predictors of mortality were functional dependence and cognitive impairment before admission, high APACHE II score and low body mass index |
Tang et al. (2003) [11] | 365 ICU patients on mechanical ventilation | Prospective cohort study | ≥ 65 years (n = 206) and <65 years (n = 159) | Severity of acute illness and chronic co-morbidities, but not age, were predictors of medical ICU and hospital mortality in elderly ventilated patients |
Chelluri et al. (2004) [43] | 817 ICU patients on mechanical ventilation | Prospective cohort study | Mean age 65 years | Long-term mortality rate was associated with old age and poor pre-hospitalization functional status |
Esteban et al. (2004) [62] | 5183 ICU patients on mechanical ventilation | International prospective cohort study | >70 years (n = 1612) | Patients older than 70 years had higher in-hospital mortality (55%) but similar duration of mechanical ventilation and length of stay |
Boumendil et al. (2004) [5] | 233 ICU patients aged 80 years and older | Prospective cohort study | >80 years | Long-term survival after ICU stay was mainly related to the underlying condition and preadmission functional status |
Vosylius et al. (2004) [63] | 2067 ICU patients | Prospective observational cohort study | >75 years (n = 477) | Mortality in elderly patients was higher than in younger patients; most important risk factors were severity of illness, impaired level of conciousness and infection. |