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Table 4 Effects of pulse high-volume haemofiltration on metabolic variables

From: Pulse high-volume haemofiltration for treatment of severe sepsis: effects on hemodynamics and survival

Variables

Pre-PHVHF

End-PHVHF

12 hours after PHVHF

P

Blood urea nitrogen (mg/dl)

102.5 (80.5–150.5)

86.0 (68.5–109.0)*

94.0 (69.0–138.0)*

<0.0001

Creatinine (mg/dl)

2.5 (1.4–3.5)

1.8 (1.2–2.9)*

1.9 (1.2–2.8)*

<0.0001

pH

7.38 (7.34–7.45)

7.40 (7.35–7.46)

7.39 (7.33–7.45)

NS

HCO3- (mmol/l)

23.9 (21.3–25.9)

24.0 (22.4–25.4)

24.0 (22.1–25.7)

NS

  1. Reported values are median (25th to 75th percentiles); P values determined using Friedman's two-way analysis of varience with post-hoc Wilcoxon signed rank test. *P < 0.0001 versus baseline. PHVHF, pulse high volume haemofiltration.