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Table 4 Effects of pulse high-volume haemofiltration on metabolic variables

From: Pulse high-volume haemofiltration for treatment of severe sepsis: effects on hemodynamics and survival

Variables Pre-PHVHF End-PHVHF 12 hours after PHVHF P
Blood urea nitrogen (mg/dl) 102.5 (80.5–150.5) 86.0 (68.5–109.0)* 94.0 (69.0–138.0)* <0.0001
Creatinine (mg/dl) 2.5 (1.4–3.5) 1.8 (1.2–2.9)* 1.9 (1.2–2.8)* <0.0001
pH 7.38 (7.34–7.45) 7.40 (7.35–7.46) 7.39 (7.33–7.45) NS
HCO3- (mmol/l) 23.9 (21.3–25.9) 24.0 (22.4–25.4) 24.0 (22.1–25.7) NS
  1. Reported values are median (25th to 75th percentiles); P values determined using Friedman's two-way analysis of varience with post-hoc Wilcoxon signed rank test. *P < 0.0001 versus baseline. PHVHF, pulse high volume haemofiltration.