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Table 3 Calculated-delivered urea clearance correlation

From: In vivo validation of the adequacy calculator for continuous renal replacement therapies

Parameter

KCALC - KDEL (ml min-1)

r

Total

-1.7 ± 5.9

0.97

   CVVHpost

-2 ± 4.3

0.96

   CVVHpre

1.4 ± 6

0.96

   CVVHD

-4.5 ± 7.7

0.97

   CVVHDF

-1.8 ± 5.3

0.98

Subgroups

  

   KCALC < 60 ml min-1

0.05 ± 3.3

0.95

   KCALC > 60 ml min-1

-5.2 ± 8.2a

0.89

   KCALC at T0

-1.04 ± 6.3

0.97

   KCALC at T18

-2.8 ± 5.2

0.96

   KCALC < 60 ml min-1 at T0

0.4 ± 3.6

0.95

   KCALC > 60 ml min-1 at T0

-4.8 ± 9.7a

0.87

   KCALC < 60 ml min-1 at T18

-0.6 ± 2.9

0.94

   KCALC > 60 ml min-1 at T18

-5.5 ± 6.5a

0.89

Delivered spKt/V

1.25 ± 0.6

 

Delivered/prescribed

0.89

 
  1. aP < 0.05 (referred to total KCALC - KDEL difference).
  2. Where errors are given, results are means ± SD. CVVH, continuous veno-venous hemofiltration; CVVHD, continuous veno-venous hemodialysis; CVVHDF, continuous veno-venous hemodiafiltration; KCALC, calculator-estimated urea clearance; KDEL, delivered clearance evaluated from urea concentrations on simultaneous blood and effluent samples; T0, therapy start; T18, 18 to 24 hours of uninterrupted therapy.
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Critical Care

ISSN: 1364-8535