Influence of support on intra-abdominal pressure, hepatic kinetics of indocyanine green and extravascular lung water during prone positioning in patients with ARDS: a randomized crossover study

Table 2 Respiratory and hemodynamic parameters

Parameter	Foam mattress			Specialist mattress			ANOVA
	Baseline	PP, 1 h	PP, 6 h	Baseline	PP, 1 h	PP, 6 h	Time	Group	Interaction
PaO₂/FiO₂	142 ± 63	178 ± 73	217 ± 69*	143 ± 44	206 ± 127*	243 ± 80*	P < 0.001	NS	NS
PaO₂ (mmHg)	45 ± 9	44 ± 9	44 ± 1 0	45 ± 6	46 ± 10	44 ± 11	NS	NS	NS
Q_VA/Q_T (%)	37 ± 8	37 ± 9	35 ± 9*	37 ± 8	36 ± 10	34 ± 10*	P < 0.05	NS	NS
Paw (cmH₂O)	18 ± 3.5	18.2 ± 3	18 ± 3	19 ± 4	19 ± 4	18.4 ± 4	NS	NS	NS
Cst (ml/cmH₂O)	38.4 ± 10	35.4 ± 8*	37.1 ± 9	38.6 ± 11	35.8 ± 8*	37 ± 8	P = 0.007	NS	NS
MPAP (mmHg)	27 ± 4	32 ± 7	30 ± 6	27 ± 4	31 ± 7	32 ± 7	NS	NS	NS
PAOP (mmHg)	12.2 ± 3.0	16.7 ± 4.0*	15.7 ± 4.0*	12.5 ± 5.0	15.8 ± 4.0*	15.9 ± 4.0*	P = 0.02	NS	NS
CVP (mmHg)	9.6 ± 4.1	13.7 ± 4	13.1 ± 5	9.4 ± 6	13 ± 5.0	13.5 ± 5.0	P = 0.02	NS	NS
CI (l/min per m²)	4.3 ± 1.1	4.3 ± 1.2	4 ± 0.9	4.5 ± 0.9	4.1 ± 1.3	4.1 ± 0.9	NS	NS	NS
EVLWI (ml/kg per m²)	11.2 ± 6.0	11.1 ± 6.2	10 ± 6.5	11.5 ± 7.3	9.5 ± 6.2	10.6 ± 6.0	NS	NS	NS
ITBV (ml)	1140 ± 475	1100 ± 535	942 ± 330	1165 ± 435	972 ± 205	985 ± 225	NS	NS	NS

Values are expressed as mean ± SD.
ANOVA, analysis of variance; CI, cardiac index; Cst, respiratory static compliance; CVP, central venous pressure; EVLWI, indexed extravascular lung water; FiO2, fraction of inspired oxygen; ITBV, intrathoracic blood volume; MPAP, mean pulmonary arterial pressure; PaCO2, arterial CO2 tension; PaO2, arterial oxygen tension; PAOP, pulmonary artery occlusion pressure; Paw, plateau airway pressure; PP, prone positioning; QVA/QT, venous admixture. *P < 0.05 compared with baseline by Tukey's post-hoc test.

ISSN: 1364-8535