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Figure 4 | Critical Care

Figure 4

From: Tezosentan-induced attenuation of lung injury in endotoxemic sheep is associated with reduced activation of protein kinase C

Figure 4

Plasma concentration of endothelin-1 (ET-1), tumor necrosis factor-α (TNF-α) and interleukin-8 (IL-8). Results are means ± SEM. Groups were as follows: sham-operated group (n = 3); lipopolysaccharide group (LPS; n = 7); LPS plus tezosentan group (n = 7). ND, not detectable. †P < 0.05 between sham-operated and LPS groups; ‡P < 0.05 between LPS and LPS plus tezosentan groups; *P < 0.05 between sham-operated and LPS plus tezosentan groups; &P < 0.05 from t = 0 hours in the LPS group; §P < 0.05 from t = 0 hours in the tezosentan group.

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