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Table 4 Exposure to study drug for all patients treated

From: Decreased duration of mechanical ventilation when comparing analgesia-based sedation using remifentanil with standard hypnotic-based sedation for up to 10 days in intensive care unit patients: a randomised trial [ISRCTN47583497]

Parameter

Remifentanil (n = 57)

Fentanyl (n = 30)

Morphine (n = 7)

Mean duration of infusion (h)

147.2

126.4

120.5

Mean total opioid dose

221,614 μg

20,702 μg

237.5 mg

Mean weighted mean opioid infusion rate(SD)

19.2a (12.2) μg kg-1 h-1

3.0 (3.35) μg kg-1 h-1

0.042 (0.028) mg kg-1 h-1

  1. aEquivalent to 0.32 μg kg-1 min-1.
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Critical Care

ISSN: 1364-8535