| Measures | Quantitation | Accuracy* | Reproducibility (COV) | Sensitivity†|
---|
CXR | LD | Poor | Unknown | Unknown | Moderate |
CT | LD | Excellent | Unknown‡ | Unknown‡ | High |
NMR | TLW | Fair | Underestimates by -40%§ | 5-10% | Poor¶ |
PET | EVLW | Excellent | Underestimates by 10-15% | < 5% | High |
ID | EVLW | Good-excellent | Overestimates by 10-20%# | 4-8% | Moderate |
- *None of the methods can distinguish whether anincrease in extravascular lung water (EVLW) represents non-cellular pulmonaryedema or cellular water from an inflammatory infiltrate.†Sensitivity to change. ‡Presumablyexcellent, but formal studies never performed. §Theunderestimates are primarily in normal or mildly edematous lungs.¶The poor sensitivity is primarily in normal or mildlyedematous lungs. #The overestimation is primarily in normal ormildly edematous lungs. TLW, total lung water (of a region on an image); LD,lung density; COV, coefficient of variation; CXR, chest X-ray; CT, computedtomography; NMR, nuclear magnetic resonance; PET, positron emission tomography;ID, indicator dilution methods.