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Table 1

From: The removal of antibiotics during continuous venovenous hemofiltration (CVVH) in critically ill patients with acute renal failure: measured versus estimated CVVH clearance

Drug (n)

Measured SC

Measured ClCVVH

Non-protein-bound fraction

Estimated ClCVVH

Ceftazidim (4)

2.14 ± 2.64

75 ± 92

0.79

28 ± 1

Ciprofloxacine (16)

0.89 ± 0.33

31 ± 12

0.60

21 ± 1

Flucloxacilline (5)

0.37 ± 0.38

13 ± 14

0.20

7 ± 0

Fluconazol (9)

0.86 ± 0.09

30 ± 2

0.88

31 ± 1

Vancomycine (6)

0.71 ± 0.19

27 ± 5

0.70

28 ± 9

  1. SC, sieving coefficient; ClCVVH, continuous venovenous hemofiltration clearance.