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Table 2 Comparison of studies of renal replacement therapy (RRT) in the management of myoglobinuric acute renal failure

From: Myoglobin clearance by super high-flux hemofiltration in a case of severe rhabdomyolysis: a case report

Reference Subject(s) Mode of RRT Filter used Sieving coefficient (%) Myoglobin removal (g/day) Clearance (ml/min)
Present study Single patient with ARF due to rhabdomyolysis CVVH, 2 l exchange Polysulphone (APS) <0.23 1.1 <8
   SHF CVVH, 3–4 l exchange Gambro Polyflux P2SH 0.69–0.72 4.3–5.1 30.5–39.2
[8] Three patients with myoglobinuric ARF Continuous hemodiafiltration Hospal AN 69S 0.21* 1.8 4.6
[9] Swine model of myoglobinuric ARF CAVH Hospal AN 69S 0.15 1.64 (0.41 g/6 hours) 1.42 ± 1.03
[10] Swine model CVVH Hospal AN 69HF 0.36–0.55 2.3–3.8 (0.95 g/6 hours) 11.2–25.2
[11] Single patient with ARF due to rhabdomyolysis CVVH Hospal AN69 Multiflow 100 0.40–0.60 1.05 (0.7 g/16 hours) 14–22
[19] Patient with malignant hyperthermia and rhabdomyolysis CVVH Gambro polyflux 11S 0.37 4.3 11*
  1. ARF, acute renal failure; CAVH, continuous arterio-venous haemofiltration; CVVH, continuous veno-venous haemofiltration; SHF, super high-flux. * Calculated from the CUF, VUF, and Cpre values provided in these studies