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Table 3 Demographics, baseline patient characteristics and outcomes of ARDS and non-ARDS patients stratified by history of chronic alcohol abuse

From: Extravascular lung water in patients with severe sepsis: a prospective cohort study

 

Non-ARDS

ARDS

 

Chronic alcohol abuse (n = 8)

Nonalcoholic (n = 6)

P

Chronic alcohol abuse (n = 8)

Nonalcoholic (n = 6)

P

EVLW (ml/kg)

7.0 (5.0–8.0)

6.5 (4.8–8.8)

NS

20.3 (16.0–26.7)

9.5 (7.1–15.4)

0.009

Source (n [% pulmonary])

2/8 (25%)

1/6 (17%)

NS

5/5 (100%)

7/10 (70%)

0.17

APACHE II score

28.7 ± 9.3

26.5 ± 7.7

NS

27.0 ± 6.7

22.4 ± 6.1

NS

PaO2/FiO2 index (mmHg)

369.7 ± 140.8

215.7 ± 116.7

NS

96.7 ± 21.7

148.0 ± 95.1

NS

LIS

0.9 ± 0.6

0.8 ± 0.7

NS

3.2 ± 0.5

2.4 ± 1.4

NS

CXR score

0.5 (0.0–1.3)

1.0 (0.5–1.5)

NS

4.0 (2.5–4.0)

3.5 (2.5–4.0)

NS

GEDV index (ml/m2)

750.3 ± 142.7

681.7 ± 81.6

NS

714.7 ± 149.7

614.2 ± 197.9

NS

Fluid balance (prior 24 hours; ml)

4703 ± 3310

6004 ± 6064

NS

4758 ± 3240

1504 ± 1550

0.03

28-Day mortality (n [%])

4/8 (50%)

1/6 (17%)

0.19

3/5 (60%)

4/10 (40%)

NS

  1. Extravascular lung water (EVLW), Acute Physiology and Chronic Health Evaluation (APACHE) II, arterial oxygen tension (PaO2)/fractional inspired oxygen (FiO2) ratio, Lung Injury Score (LIS), and chest radiographic (CXR) score are initial values calculated from study day 1. Values are expressed as means ± standard deviation or as median (interquartile range). ARDS, acute respiratory distress syndrome.