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Table 3 Demographics, baseline patient characteristics and outcomes of ARDS and non-ARDS patients stratified by history of chronic alcohol abuse

From: Extravascular lung water in patients with severe sepsis: a prospective cohort study

  Non-ARDS ARDS
  Chronic alcohol abuse (n = 8) Nonalcoholic (n = 6) P Chronic alcohol abuse (n = 8) Nonalcoholic (n = 6) P
EVLW (ml/kg) 7.0 (5.0–8.0) 6.5 (4.8–8.8) NS 20.3 (16.0–26.7) 9.5 (7.1–15.4) 0.009
Source (n [% pulmonary]) 2/8 (25%) 1/6 (17%) NS 5/5 (100%) 7/10 (70%) 0.17
APACHE II score 28.7 ± 9.3 26.5 ± 7.7 NS 27.0 ± 6.7 22.4 ± 6.1 NS
PaO2/FiO2 index (mmHg) 369.7 ± 140.8 215.7 ± 116.7 NS 96.7 ± 21.7 148.0 ± 95.1 NS
LIS 0.9 ± 0.6 0.8 ± 0.7 NS 3.2 ± 0.5 2.4 ± 1.4 NS
CXR score 0.5 (0.0–1.3) 1.0 (0.5–1.5) NS 4.0 (2.5–4.0) 3.5 (2.5–4.0) NS
GEDV index (ml/m2) 750.3 ± 142.7 681.7 ± 81.6 NS 714.7 ± 149.7 614.2 ± 197.9 NS
Fluid balance (prior 24 hours; ml) 4703 ± 3310 6004 ± 6064 NS 4758 ± 3240 1504 ± 1550 0.03
28-Day mortality (n [%]) 4/8 (50%) 1/6 (17%) 0.19 3/5 (60%) 4/10 (40%) NS
  1. Extravascular lung water (EVLW), Acute Physiology and Chronic Health Evaluation (APACHE) II, arterial oxygen tension (PaO2)/fractional inspired oxygen (FiO2) ratio, Lung Injury Score (LIS), and chest radiographic (CXR) score are initial values calculated from study day 1. Values are expressed as means ± standard deviation or as median (interquartile range). ARDS, acute respiratory distress syndrome.