Table 1 Baseline demographic characteristics and outcomes for all patients with severe sepsis
From: Extravascular lung water in patients with severe sepsis: a prospective cohort study
| ARDS | Non-ARDS | Total | |
|---|---|---|---|
| Patients (n) | 15 | 14 | 29 |
| Baseline characteristics | |||
| Age (years) | 44 ± 12 | 57 ± 14 | 51 ± 15* |
| Sex (male) | 5/15 | 5/14 | 10/29 |
| Race (African American/Caucasian/other) | 12/3/0 | 12/0/2 | 24/3/2 |
| Chronic heart disease | 1/15 | 2/14 | 3/29 |
| Chronic obstructive lung disease | 1/15 | 1/15 | 2/29 |
| Chronic renal disease (serum creatinine ≥ 2.0 mg/dl) | 1/15 | 3/14 | 4/29 |
| HIV infection | 7/15 | 4/14 | 11/29 |
| Chronic alcohol abuse | 5/15 | 8/14 | 13/29 |
| Bacteremia | 7/15 | 5/14 | 12/29 |
| APACHE II score (day 1) | 23.9 ± 6.5 | 27.7 ± 8.3 | 25.7 ± 7.5 |
| Mechanically ventilated | 14/15 | 11/14 | 25/29 |
| Physiology at enrollment | |||
| White blood cell count (cells × 103/ml) | 20.4 (10.8–30.0) | 13.6 (3.8–23.4) | 17.2 (8.9–25.5) |
| Prior 24-hour fluid balance (ml) | 2506 ± 2583 | 4993 ± 3625 | 3523 ± 3223 |
| Shock (vasopressor requirement) | 12/15 | 10/14 | 22/29 |
| Cardiac index (l/min per m2) | 3.8 ± 1.0 | 4.3 ± 1.4 | 4.0 ± 1.2 |
| GEDV index (ml/m2) | 648 ± 184 | 719 ± 119 | 681 ± 159 |
| SVRI (dyn·s/cm5 per m2) | 1408 ± 441 | 1668 ± 669 | 1528 ± 562 |
| EVLW index (ml/kg) | 15.0 (9.0–16.7) | 7.0 (5.0–8.2) | 8.5 (5.1–15.8)* |
| Outcome | |||
| ICU length of stay (days) | 14.0 (8.5–21.0) | 10.0 (4.8–16.3) | 13.0 (7.0–17.0) |
| Hospital length of stay (days) | 26.0 (12.3–42.3) | 19.0 (16.0–31.0) | 19.0 (13.0–36.0) |
| 28-day mortality | 7/15 | 5/14 | 12/29 |