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Table 1 Baseline demographic characteristics and outcomes for all patients with severe sepsis

From: Extravascular lung water in patients with severe sepsis: a prospective cohort study

  ARDS Non-ARDS Total
Patients (n) 15 14 29
Baseline characteristics
   Age (years) 44 ± 12 57 ± 14 51 ± 15*
   Sex (male) 5/15 5/14 10/29
   Race (African American/Caucasian/other) 12/3/0 12/0/2 24/3/2
   Chronic heart disease 1/15 2/14 3/29
   Chronic obstructive lung disease 1/15 1/15 2/29
   Chronic renal disease (serum creatinine ≥ 2.0 mg/dl) 1/15 3/14 4/29
   HIV infection 7/15 4/14 11/29
   Chronic alcohol abuse 5/15 8/14 13/29
   Bacteremia 7/15 5/14 12/29
   APACHE II score (day 1) 23.9 ± 6.5 27.7 ± 8.3 25.7 ± 7.5
   Mechanically ventilated 14/15 11/14 25/29
Physiology at enrollment
   White blood cell count (cells × 103/ml) 20.4 (10.8–30.0) 13.6 (3.8–23.4) 17.2 (8.9–25.5)
   Prior 24-hour fluid balance (ml) 2506 ± 2583 4993 ± 3625 3523 ± 3223
   Shock (vasopressor requirement) 12/15 10/14 22/29
   Cardiac index (l/min per m2) 3.8 ± 1.0 4.3 ± 1.4 4.0 ± 1.2
   GEDV index (ml/m2) 648 ± 184 719 ± 119 681 ± 159
   SVRI (dyn·s/cm5 per m2) 1408 ± 441 1668 ± 669 1528 ± 562
   EVLW index (ml/kg) 15.0 (9.0–16.7) 7.0 (5.0–8.2) 8.5 (5.1–15.8)*
Outcome
   ICU length of stay (days) 14.0 (8.5–21.0) 10.0 (4.8–16.3) 13.0 (7.0–17.0)
   Hospital length of stay (days) 26.0 (12.3–42.3) 19.0 (16.0–31.0) 19.0 (13.0–36.0)
   28-day mortality 7/15 5/14 12/29
  1. Values are expressed as mean ± standard deviation, frequency (%), or median (interquartile range), unless otherwise noted.
  2. * P for difference between groups < 0.05. APACHE, Acute Physiology and Chronic Health Evaluation; ARDS, acute respiratory distress syndrome; EVLW, extravascular lung water; GEDV, global end-diastolic volume; ICU, intensive care unit; SVRI, systemic vascular resistance index.