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Table 2 Arterial hemoglobin, acid-base and metabolic parameters in sham, normal and increased blood flow groups

From: Increased blood flow prevents intramucosal acidosis in sheep endotoxemia: a controlled study

Parameter Group Basal Endotoxemia
    30 min 60 min 90 min 120 min
Hemoglobin (g/l) Sham 9.6 ± 2.4 9.7 ± 2.7 9.9 ± 2.3 9.8 ± 2.2 9.9 ± 2.2
  Normal 9.1 ± 2.3 9.0 ± 2.4 8.4 ± 2.0* 8.1 ± 2.2* 8.3 ± 2.4*
  Increased 8.9 ± 2.2 8.2 ± 2.3* 7.8 ± 2.4* 7.6 ± 2.5* 7.7 ± 2.5*
pH Sham 7.44 ± 0.03 7.45 ± 0.02 7.45 ± 0.03 7.47 ± 0.02 7.47 ± 0.03
  Normal 7.39 ± 0.07 7.34 ± 0.08*† 7.31 ± 0.05*† 7.34 ± 0.05*† 7.35 ± 0.06*†
  Increased 7.42 ± 0.04 7.35 ± 0.05*† 7.31 ± 0.05*† 7.28 ± 0.08*† 7.25 ± 0.08*†‡
PCO2 (mmHg) Sham 35 ± 3 34 ± 3 34 ± 3 33 ± 3 34 ± 4
  Normal 35 ± 4 38 ± 6* 41 ± 7* 37 ± 6 35 ± 6
  Increased 34 ± 2 36 ± 5 34 ± 3 34 ± 5 37 ± 6
PO2 (mmHg) Sham 85 ± 13 88 ± 18 86 ± 16 88 ± 17 84 ± 15
  Normal 87 ± 16 119 ± 59 105 ± 39 123 ± 20*† 134 ± 43*†
  Increased 90 ± 23 150 ± 48*† 132 ± 21*† 101 ± 20 99 ± 31
[HCO3-] (mmol/l) Sham 24 ± 2 24 ± 3 24 ± 3 24 ± 3 24 ± 3
  Normal 21 ± 2 21 ± 2 20 ± 2† 20 ± 2*† 19 ± 2*†
  Increased 22 ± 3 20 ± 2*† 17 ± 3*† 16 ± 3*†‡ 16 ± 2*†‡
Base excess (mmol/l) Sham 1 ± 3 1 ± 3 1 ± 3 2 ± 3 2 ± 3
  Normal t2 ± 4 t5 ± 3*† t5 ± 2*† t5 ± 3*† t5 ± 3*†
  Increased t1 ± 4 t4 ± 3*† t8 ± 4*† t10 ± 4*† t10 ± 3*†‡
[Cl-]/[Na+] Sham 0.76 ± 0.02   0.76 ± 0.03   0.76 ± 0.03
  Normal 0.76 ± 0.01   0.77 ± 0.02   0.77 ± 0.01
  Increased 0.76 ± 0.02   0.78 ± 0.02*   0.80 ± 0.02*†‡
Lactate (mmol/l) Sham 2.1 ± 0.7   2.0 ± 0.7   1.8 ± 0.6
  Normal 1.7 ± 0.8   1.9 ± 0.7   2.2 ± 1.1
  Increased 2.2 ± 1.6   1.7 ± 1.1   1.9 ± 1.1
  1. * P < 0.05 versus basal. † P < 0.05 versus sham. ‡ P < 0.05 versus normal. Sham, sham group; normal, normal blood flow group; increased, increased blood flow group.