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Table 1 Systemic and intestinal hemodynamic and oxygen transport parameters in sham, normal and increased blood flow groups

From: Increased blood flow prevents intramucosal acidosis in sheep endotoxemia: a controlled study

Parameter Group Basal Endotoxemia
    30 min 60 min 90 min 120 min
Mean arterial pressure (mmHg) Sham 81 ± 10 85 ± 15 88 ± 15 91 ± 16 92 ± 19
  Normal 93 ± 19 89 ± 25 83 ± 23 91 ± 32 94 ± 26
  Increased 90 ± 17 98 ± 17 89 ± 18 89 ± 21 99 ± 17
Mean pulmonary arterial pressure (mmHg) Sham 16 ± 3 15 ± 3 16 ± 3 15 ± 4 16 ± 4
  Normal 15 ± 5 34 ± 9*† 26 ± 8*† 25 ± 7*† 24 ± 6*†
  Increased 20 ± 4 35 ± 10*† 31 ± 4*† 34 ± 6*†‡ 35 ± 6*†‡
Pulmonary wedge pressure (mmHg) Sham 5 ± 2 5 ± 2 5 ± 1 5 ± 2 5 ± 2
  Normal 5 ± 2 11 ± 4*† 8 ± 2*† 8 ± 3*† 8 ± 4
  Increased 6 ± 1 11 ± 4*† 13 ± 6*† 12 ± 3*† 14 ± 5*†‡
Central venous pressure (mmHg) Sham 5 ± 5 5 ± 3 6 ± 5 5 ± 4 5 ± 4
  Normal 4 ± 2 5 ± 3 6 ± 2 6 ± 2 5 ± 3
  Increased 4 ± 2 8 ± 3 9 ± 5* 10 ± 4*†‡ 11 ± 4*†‡
Cardiac output (ml/kg per min) Sham 134 ± 30 148 ± 36 153 ± 37 144 ± 33 151 ± 41
  Normal 139 ± 43 117 ± 27 135 ± 38 149 ± 42 142 ± 34
  Increased 157 ± 51 221 ± 64*†‡ 257 ± 67*†‡ 276 ± 84*†‡ 290 ± 91*†‡
Superior mesenteric artery blood flow (ml/min per g) Sham 498 ± 107 568 ± 126* 551 ± 126* 548 ± 134* 539 ± 131*
  Normal 553 ± 184 514 ± 152 566 ± 161 573 ± 145 529 ± 169
  Increased 578 ± 206 803 ± 226*‡ 794 ± 209*†‡ 863 ± 326*‡ 923 ± 370*†‡
  Increased 362 ± 116 437 ± 75†‡ 286 ± 53 336 ± 102 295 ± 75
Systemic oxygen transport (ml/min per kg) Sham 16.2 ± 4.5 18.0 ± 5.6* 19.0 ± 6.2* 17.8 ± 5.3 18.8 ± 6.1*
  Normal 16.4 ± 6.6 13.3 ± 4.9 14.0 ± 4.8 16.4 ± 6.4 15.8 ± 5.7
  Increased 17.2 ± 4.0 23.0 ± 5.5*‡ 25.5 ± 6.7*‡ 26.0 ± 8.4*‡ 26.9 ± 9.9*‡
Systemic oxygen consumption (ml/min per kg) Sham 6.4 ± 0.8 6.4 ± 1.1 6.8 ± 1.3 6.6 ± 1.2 7.2 ± 1.3
  Normal 6.4 ± 1.2 5.3 ± 1.2* 5.8 ± 1.6* 6.0 ± 1.5 6.5 ± 1.4
  Increased 7.6 ± 0.9 7.6 ± 2.0‡ 7.3 ± 2.1 7.4 ± 2.2 8.3 ± 3.2
Intestinal oxygen transport (ml/min per kg) Sham 62.3 ± 22.2 71.4 ± 24.8* 70.8 ± 25.1* 69.9 ± 24.6* 69.1 ± 24.0*
  Normal 64.0 ± 22.6 56.1 ± 19.3 57.0 ± 15.8 60.8 ± 18.4 56.5 ± 17.0
  Increased 64.3 ± 16.7 86.4 ± 19.1*‡ 81.4 ± 22.1* 82.2 ± 23.5* 87.1 ± 23.6*‡
Intestinal oxygen consumption (ml/min per kg) Sham 21.7 ± 4.0 21.1 ± 3.7 22.0 ± 3.2 22.7 ± 4.2 21.8 ± 4.7
  Normal 21.2 ± 4.1 22.1 ± 6.5 22.7 ± 8.9 22.6 ± 7.8 22.4 ± 9.0
  Increased 29.3 ± 9.7 28.9 ± 9.3 32.5 ± 13.0 29.8 ± 9.4 37.2 ± 12.3†‡
  1. * P < 0.05 versus basal. † P < 0.05 versus sham. ‡ P < 0.05 versus normal. Sham, sham group; normal, normal blood flow group; increased, increased blood flow group.