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Table 1 Characteristics, indications for surgery and outcome of patients operated on for severe acute pancreatitis (n = 56)

From: Perioperative factors determine outcome after surgery for severe acute pancreatitis

Parameter

Early surgerya (n = 22)

Late surgerya (n = 34)

P

Patient characteristics

   Age, years (mean ± SD)

54 ± 14.8

56 ± 12.8

0.58

   Male sex

16 (72.7%)

19 (55.9%)

0.20

   APACHE II score (mean ± SD)

22 ± 12.1

19 ± 8.9

0.47

   Ranson score (mean ± SD)

6.2 ± 2.46

5.8 ± 1.80

0.59

   Sterile necrosis at first surgical intervention

13 (59.1%)

17 (50%)

0.50

   Interval from diagnosis to surgery, days (median and IQR)

5 (3–9)

20 (17–31)

<0.001

   SOFA score at surgical intervention (median and IQR)

4 (2–8)

4 (2–8)

0.78

Indications for surgery

   Documented infection of pancreatic necrosis

5 (22.7%)

14 (41.2%)

0.25

   Deteriorating clinical condition

9 (40.9%)

3 (8.8%)

0.007

   Unresolving pancreatitis or suspected infection of pancreatic necrosis

8 (36.4%)

17 (50%)

0.41

Outcome

   LOS in ICU, days (median and IQR)

14 (5–33)

14 (6–35)

0.75

   LOS in hospital, days (median and IQR)

29 (15–58)

87 (54–106)

<0.001

   LOS in ICU in hospital survivors, days (median and IQR)b

16 (4–46)

12 (5–31)

0.92

   LOS in hospital in hospital survivors, days (median and IQR)b

44 (30–107)

88 (60–106)

0.034

   Mortality

12 (54.5%)

10 (29.4%)

0.06

  1. APACHE II score, Acute Physiology And Chronic Health Evaluation II score; ICU, intensive care unit; IQR, interquartile range; LOS, length of stay; SOFA, sepsis-related organ failure assessment.
  2. aEarly surgery was defined as surgery within the first 12 days after admission.
  3. bEarly surgery, n = 10; late surgery, n = 24.