From: Perioperative factors determine outcome after surgery for severe acute pancreatitis
Parameter | Early surgerya (n = 22) | Late surgerya (n = 34) | P |
---|---|---|---|
Patient characteristics | |||
   Age, years (mean ± SD) | 54 ± 14.8 | 56 ± 12.8 | 0.58 |
   Male sex | 16 (72.7%) | 19 (55.9%) | 0.20 |
   APACHE II score (mean ± SD) | 22 ± 12.1 | 19 ± 8.9 | 0.47 |
   Ranson score (mean ± SD) | 6.2 ± 2.46 | 5.8 ± 1.80 | 0.59 |
   Sterile necrosis at first surgical intervention | 13 (59.1%) | 17 (50%) | 0.50 |
   Interval from diagnosis to surgery, days (median and IQR) | 5 (3–9) | 20 (17–31) | <0.001 |
   SOFA score at surgical intervention (median and IQR) | 4 (2–8) | 4 (2–8) | 0.78 |
Indications for surgery | |||
   Documented infection of pancreatic necrosis | 5 (22.7%) | 14 (41.2%) | 0.25 |
   Deteriorating clinical condition | 9 (40.9%) | 3 (8.8%) | 0.007 |
   Unresolving pancreatitis or suspected infection of pancreatic necrosis | 8 (36.4%) | 17 (50%) | 0.41 |
Outcome | |||
   LOS in ICU, days (median and IQR) | 14 (5–33) | 14 (6–35) | 0.75 |
   LOS in hospital, days (median and IQR) | 29 (15–58) | 87 (54–106) | <0.001 |
   LOS in ICU in hospital survivors, days (median and IQR)b | 16 (4–46) | 12 (5–31) | 0.92 |
   LOS in hospital in hospital survivors, days (median and IQR)b | 44 (30–107) | 88 (60–106) | 0.034 |
   Mortality | 12 (54.5%) | 10 (29.4%) | 0.06 |